UniProtKB/Swiss-Prot PTM Description

Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity

Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif N- and O-glycosylated. Isoform 5 is GalNAc O-glycosylated at Thr-59 or Ser-62

Glycan Structures

Notes

Accompanying information

Structure Format

CFG/Essentials Text Oxford

Sequence

MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN

References 2

  1. N-Glycan structures of an osteopontin from human bone.

    Masuda K, Takahashi N, Tsukamoto Y, Honma H, Kohri K

    PubMed: 10679288 Year: 2000

  2. N-Glycan structures of an osteopontin from human bone.

    Masuda K, Takahashi N, Tsukamoto Y, Honma H, Kohri K

    PubMed: 10679288 Year: 2000